Spravato is a nasal spray form of esketamine. Most antidepressants target serotonin or norepinephrine; Spravato acts on the glutamate system instead, giving people who haven't responded to other medications a different route to relief.

Adults with major depressive disorder who have tried at least two antidepressants without enough improvement, or adults with depression who are experiencing suicidal thoughts or actions. Certain conditions, such as some blood vessel disorders or a history of bleeding in the brain, may rule it out. Emily will review your full history first.

Often, yes. Spravato is commonly used alongside an oral antidepressant, though your plan will be tailored to you. Never stop or change a medication without talking with your provider.

Some people feel drowsy, dizzy, or briefly detached or "floaty" after a dose. These effects usually peak soon after the dose and fade within the monitoring period. Our team stays with you and checks on you throughout.

No. You'll need someone to drive you home after each session, and you shouldn't drive or operate machinery until the next day after a restful night's sleep.

The most common include dissociation, dizziness, nausea, sleepiness, a spinning sensation, numbness, anxiety and a temporary rise in blood pressure. We check your blood pressure before and after each dose.

Typically twice weekly for the first four weeks, once weekly for weeks five through eight, then weekly or every other week after that, depending on your response.

SPRAVATO® is covered by many insurance plans, although coverage and out-of-pocket costs may vary. Depending on your plan, you may be responsible for a visit copay and/or medication copay. Before approving treatment, most insurance providers require a list of antidepressant medications you have previously tried. We recommend having this information available before your initial consultation to help streamline the approval process. Our team is happy to answer any questions and help you navigate your insurance coverage.